Informasi ringkas dokumen repository.
| Advisor(s) | Rahmi, Sofia | |
| Author(s) | DEWI, VIOLA FRANSETYA | |
| Issued Date | 2026 | |
| Abstract | Menstrual pain (dysmenorrhea) is a common complaint among adolescent girls that can interfere with daily activities. This study aimed to formulate and evaluate a nutraceutical cookie product containing *Sechium edule* Jacq. (chayote) nanosimplisia and to observe the reduction of menstrual pain in adolescent girls. The study was conducted experimentally, involving the preparation of nanosimplisia, particle characterization, formulation of cookies with varying concentrations, physical quality evaluation, hedonic testing, and the assessment of menstrual pain using the Numeric Rating Scale (NRS). Characterization results showed particle sizes of 322.17 ± 12.28 nm for F0, 170.63 ± 24.71 nm for F1, 205.10 ± 59.35 nm for F2, and 179.30 ± 64.59 nm for F3. Zeta potential values ranged from 30.23 to 35.53 mV, while the polydispersity index (PDI) ranged from 0.93 to 0.97. The moisture content of the cookies ranged from 3.21% to 4.12%, and none of the formulations showed organoleptic changes during a seven-day storage period. Measurements indicated an average reduction in menstrual pain of 54.03% for the mild pain group, 52.56% for moderate pain, 61.43% for severe pain, and 47.63% for very severe pain. Two-way ANOVA analysis revealed that age, initial pain level, and the interaction between the two did not have a significant effect on the percentage reduction in menstrual pain (p > 0.05). In conclusion, chayote can be formulated into nutraceutical cookies with favorable physical characteristics; however, its effectiveness in alleviating menstrual pain requires further investigation. | 1 |
| Item Type | Tesis | |
| Keywords | cookies, dismenore, labu siam (chayote), nanosimplisia, nutrasetika (nutraceuticals) | 1 |
| Collection | Fakultas Farmasi, S1-Farmasi | |
| Publisher | INSTITUT KESEHATAN DELI HUSADA DELI TUA | |
| Submitted Date | 13-11-2026 | |
| Updated Date | 13-11-2026 | |
| URI | https://repo.delihusada.mediantarakreasindo.com/handle/123456789/11333 | |
| File |
2218222_VIOLAFRANSETYADEWI_SKRIPSI_S1.pdf
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