Informasi ringkas dokumen repository.
| Advisor(s) | apt. Sofia Eliasari Br Bangun, S.Farm., M.Farm. | |
| Author(s) | HASIBUAN, FITRI DINI | |
| Issued Date | 2026 | |
| Abstract | Tinted sunscreen is a cosmetic product that functions to protect the skin from ultraviolet (UV) radiation while providing a more even skin tone. The increasing public demand for this product has raised concerns regarding the possible misuse of prohibited active pharmaceutical ingredients in cosmetic formulations, one of which is retinoic acid. Retinoic acid is classified as a prescription drug and is prohibited from being used in cosmetic products due to its potential to cause skin irritation, photosensitivity, and teratogenic effects. This study aimed to identify and determine the retinoic acid content in tinted sunscreen products marketed using Thin-Layer Chromatography (TLC) and UV-Visible Spectrophotometry method. this study used to evaluate the validity of the analytical method. This study was a descriptive experimental study involving three tinted sunscreen samples selected by purposive sampling. Qualitative identification was carried out using the TLC method, while quantitative analysis was performed using UV-Visible Spectrophotometry at a maximum wavelength of 337 nm. The results showed that all samples tested positive for retinoic acid based on the similarity of their Rf values to the reference standard. The retinoic acid contents in samples A, B, and C were 0.05699%, 0.04330%, and 0.05715%, respectively. The analytical method fulfilled the validation requirements, including linearity, accuracy, precision, Limit of Detection (LOD), and Limit of Quantification (LOQ). It can be concluded that all analyzed tinted sunscreen samples contained retinoic acid and therefore did not comply with the regulations of the Indonesian Food and Drug Authority, which prohibit the use of retinoic acid in cosmetic products. Based on the results of this study, it is suggested that further research analyze retinoic acid content in a wider range of cosmetic products using more advanced analytical methods, and increased supervision and education are needed to prevent the circulation of cosmetic products containing prohibited ingredients. Keywords: retinoic acid, tinted sunscreen, thin-layer chromatography, UV-Visible spectrophotometry, method validation. | 1 |
| Item Type | Skripsi | |
| Keywords | Asam retinoat ( Retinoid acid), Tinted sunscreen, Kromatografi lapis tipis (Thin-layer chromatography), Spektrofotometri UV-Vis ( UV-Visible spectrophotometry, Validasi metode ( Method validation). | 1 |
| Collection | Fakultas Farmasi, S1-Farmasi | |
| Publisher | INSTITUT KESEHATAN DELI HUSADA | |
| Submitted Date | 27-08-2026 | |
| Updated Date | 28-08-2026 | |
| URI | https://repo.delihusada.mediantarakreasindo.com/handle/123456789/10944 | |
| File |
2218071_FITRIDINIHASIBUAN_SKRIPSI_S1.pdf
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