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| Advisor(s) | Harahap, Nina Irmayanti | |
| Author(s) | SAGALA, YEK GLEDIES BR. | |
| Issued Date | 2026 | |
| Abstract | Henna Leaf Plant (Lawsonia Inermis L.) contains alkaloids, tannins, flavonoids, and steroids that are able to inhibit antibacterial activity. This study aims to find out the antibacterial activity of the dermal gel patch preparation of Henna Leaf Ethanol Extract (Lawsonia Inermis L.) against Cutibacterium acnes and Staphylococcus aureus bacteria at concentrations of 5%, 10%, and 15%. The making of the extract is done by maceration method using 96% ethanol. This research uses an experimental method by testing the parameters of the physical evaluation requirements of the dermal gel patch preparation. Physical evaluation of the preparation includes organoleptic test, weight uniformity test, patch thickness test, fold resistance test, pH test, moisture absorption test, and irritation test. The research results of the physical evaluation test of the Henna Leaf Ethanol Extract gel dermal patch with a concentration of 5%, 10%, and 10% are qualified. Antibacterial testing of dermal gel patch preparation, Henna Leaf Ethanol Extract using disc diffusion method, in Cutibacterium acnes bacteria can inhibit bacterial growth at concentrations of 5%, 10%, and 15% with an average inhibition zone diameter of 11.9 mm, 15.0 mm, and 17.5 with strong inhibitory categories. While in bacteria Staphylococcus aureus bacteria can inhibit the growth of Staphylococcus aureus bacteria with an average diameter of 12.0 mm, 13.1 mm, and 16.8 mm inhibition zone with a strong inhibitory category. | 1 |
| Item Type | Skripsi | |
| Keywords | Daun Henna (Lawsonia Inermis L.), Lawsonia Inermis L., Patch Dermal Gel, Dermal Gel Patch, Aktivitas Antibakteri Cutibacterium acnes, Staphylococcus aureus, Antibacterial Activity Cutibacterium acnes, Staphylococcus aures. | 1 |
| Collection | Fakultas Farmasi, S1-Farmasi | |
| Publisher | INSTITUT KESEHATAN DELI HUSADA DELI TUA | |
| Submitted Date | 06-11-2026 | |
| Updated Date | 06-11-2026 | |
| URI | https://repo.delihusada.mediantarakreasindo.com/document/file/11226/page | |
| File |
2218238_YEKGLEDIESBR.SAGALA_SKRIPSI_S1.pdf
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