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| Advisor(s) | apt. Sulasmi, S.Farm., M.K.M., M.Farm. | |
| Author(s) | Wahyuni | |
| Issued Date | 2026 | |
| Abstract | EXPOSURE TO FREE RADICALS CAN CAUSE OXIDATIVE STRESS THAT CONTRIBUTES TO VARIOUS DEGENERATIVE DISEASES. BANDOTAN LEAVES (AGERATUM CONYZOIDES L.) ARE KNOWN TO CONTAIN SECONDARY METABOLITE COMPOUNDS WITH POTENTIAL AS NATURAL ANTIOXIDANTS. THIS STUDY AIMED TO DETERMINE THE ANTIOXIDANT ACTIVITY OF ETHANOL EXTRACT OF BANDOTAN LEAVES USING THE DPPH METHOD WITH UV-VIS SPECTROPHOTOMETRY AND TO DETERMINE THE IC50 VALUE OF THE EXTRACT. THIS STUDY WAS AN EXPERIMENTAL LABORATORY STUDY. BANDOTAN LEAVES WERE EXTRACTED USING THE MACERATION METHOD WITH 96% ETHANOL. ANTIOXIDANT ACTIVITY WAS TESTED USING THE DPPH METHOD AT SEVERAL EXTRACT CONCENTRATIONS, THEN ABSORBANCE WAS MEASURED USING A UV-VIS SPECTROPHOTOMETER. THE DATA OBTAINED WERE CALCULATED AS PERCENT INHIBITION AND IC50 VALUE, THEN STATISTICALLY ANALYZED USING THE ONE-WAY ANOVA TEST. THE RESULTS SHOWED THAT THE ETHANOL EXTRACT OF BANDOTAN LEAVES HAD THE ABILITY TO INHIBIT DPPH FREE RADICALS, AS INDICATED BY AN INCREASE IN PERCENT INHIBITION WITH INCREASING EXTRACT CONCENTRATION. THE IC50 VALUE OBTAINED WAS 64.893 µG/ML, SO IT IS INCLUDED IN THE STRONG ANTIOXIDANT CATEGORY. THE ONE-WAY ANOVA TEST RESULTS SHOWED A SIGNIFICANCE VALUE OF 0.000 (P < 0.05), INDICATING THAT VARIATIONS IN THE CONCENTRATION OF ETHANOL EXTRACT OF BANDOTAN LEAVES SIGNIFICANTLY AFFECTED ANTIOXIDANT ACTIVITY. | 1 |
| Item Type | Skripsi | |
| Keywords | Ageratum conyzoides L., daun bandotan, antioksidan, DPPH, IC₅₀, spektrofotometri UV-Vis. | 1 |
| Collection | Fakultas Farmasi, S1-Farmasi | |
| Publisher | INSTITUT KESEHATAN DELI HUSADA | |
| Submitted Date | 23-10-2026 | |
| Updated Date | 23-10-2026 | |
| URI | https://repo.delihusada.ac.id/handle/123456789/11271 | |
| File |
2218227_Wahyuni_Skripsi_S1.pdf
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