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| Advisor(s) | Marbun, Novarianti | |
| Author(s) | GINTING, NESIA BESABEL BR | |
| Issued Date | 2026 | |
| Abstract | Lime leaves (Citrus aurantifolia) contain secondary metabolite compounds that have the potential to be antibacterial. This study is aimed aims to formulate nano simplicia of lime leaves into paper soap preparations, evaluate the physical quality of the preparation, and test its antibacterial activity against Escherichia coli. Nano simplisia was characterized using a Particle Size Analyzer (PSA) and a Scanning Electron Microscope (SEM), then formulated into three paper soap formulas. Evaluation of the preparation included organoleptic tests, homogeneity, pH, weight uniformity, dissolving time, and antibacterial activity by disc diffusion method. The results of the study showed that the paper soap produced had a good sheet shape, homogeneous, and met physical quality requirements. The pH value of the preparation is within the acceptable range for soaps, the uniformity of the weight meets the requirements, and the dissolving time indicate that the preparation is easy to use. The results of the antibacterial test showed that the entire formula was able to inhibit the growth of Escherichia coli, with increased inhibition as the concentration of nanosimplicia increased. The F3 formula provides the highest antibacterial activity compared to other formulas. Based on the results of the study, it can be concluded that nano simplisia lime leaves can be formulated into paper soap preparations that have good physical quality and are able to provide antibacterial activity against Escherichia coli. The F3 formula is a formula that gives the best results based on physical evaluation and antibacterial activity. | 1 |
| Item Type | Skripsi | |
| Keywords | Paper Soap (Paper Soap), Nanosimplisia (Nanosimplisia), Daun Jeruk Nipis ( Lime Leaf) (Citrus Aurantifolia), Antibakteri (Antibacterial), Escherichia Coli. | 1 |
| Collection | Fakultas Farmasi, S1-Farmasi | |
| Publisher | INSTITUT KESEHATAN DELI HUSADA | |
| Submitted Date | 06-10-2026 | |
| Updated Date | 08-10-2026 | |
| URI | No URI | |
| File |
2218125_NESIABESABELBRGINTING_SKRIPSI_S1.pdf
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