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| Advisor(s) | Purba, Gratia Apulina Cindylawsa | |
| Author(s) | KETAREN, MEYLISA FEBRIANA BR | |
| Issued Date | 2026 | |
| Abstract | Manilkara zapota L. leaves are known to contain secondary metabolites with potential antioxidant properties. This study is aimed to evaluate the antioxidant activity of the n-hexane and ethyl acetate fractions of the ethanolic extract of Manilkara zapota leaves using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, to determined the IC50 values of each fraction, and to identify the fraction with the strongest antioxidant activity. This experimental laboratory study used dried leaves extracted by maceration with 96% ethanol, followed by fractionation using n-hexane and ethyl acetate. Phytochemical screening and antioxidant activity assays were conducted using a UV–Visible spectrophotometer. The phytochemical screening results show that the n-hexane fraction contains steroids, whereas the ethyl acetate fraction contains flavonoids, alkaloids, tannins, and saponins. The antioxidant assay results show that the n-hexane fraction exhibits strong antioxidant activity, while the ethyl acetate fraction exhibits very strong antioxidant activity with an IC50 value of 5.4143 μg/mL. It is concluded that the ethyl acetate fraction has higher antioxidant activity than the n-hexane fraction and has the potential to be developed as a natural antioxidant source. | 1 |
| Item Type | Skripsi | |
| Keywords | Daun Sawo Manila (Manilkara Zapote Leaves), Antioksidan (Antioxidant), DPPH, Fraksi Etil Asetat (Ethyl Acetate Fraction), Fraksi N-heksana (N-Hexane Fraction) | 1 |
| Collection | Fakultas Farmasi, S1-Farmasi | |
| Publisher | institut kesehatan deli husada deli tua | |
| Submitted Date | 23-09-2026 | |
| Updated Date | 23-10-2026 | |
| URI | No URI | |
| File |
2218112_MEYLISAFEBRIANABRKETAREN_SKRIPSI_S1.pdf
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