POTENSI EKSTRAK METANOL DAUN BAKAU KURAP (Rhizophora mucronata L. ) SEBAGAI AGEN ANTIBAKTERI TERHADAP BAKTERI Staphylococus aureus dan Escherichia coli DENGAN METODE KROMATOGRAFI LAPIS TIPIS (KLT)

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Advisor(s) FAHDI, FIRDAUS
Author(s) SOFA, NURUS
Issued Date 2026
Abstract This study aims to determine the Thin Layer Chromatography (TLC) profile and to evaluate the antibacterial activity of methanol extract of bakau kurap leaves (Rhizophora mucronata L.) against Staphylococcus aureus and Escherichia coli bacteria in vitro. Extraction was carried out using the maceration method with methanol as the solvent. Phytochemical screening and TLC analysis showed that the methanol extract of bakau kurap leaves positively contains secondary metabolites including alkaloids, flavonoids, tannins, and triterpenoids/steroids, with an Rf value of 0.7.Antibacterial activity testing was performed using the well diffusion method with various extract concentrations. The results showed that the methanol extract of bakau kurap leaves exhibited inhibitory activity against both tested bacteria. The most effective concentration was 75%, with inhibition zone diameters of 16.89 mm against Staphylococcus aureus and 13.95 mm against Escherichia coli, which are categorized as strong antibacterial activity. Statistical analysis using One Way ANOVA indicated a significant difference between concentrations (p < 0.05). 1
Item Type Skripsi
Keywords Rhizophora mucronata (Rhizophora mucronata), antibakteri (antibacterial,), KLT (TLC), Staphylococcus aureus, Escherichia coli. 1
Collection Fakultas Farmasi, S1-Farmasi
Publisher INSTITUT KESEHATAN DELI HUSADA
Submitted Date 28-08-2026
Updated Date 29-08-2026
URI No URI
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