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| Advisor(s) | Lestari, Puji | |
| Author(s) | SIMANJUNTAK, SONIA OCTAVIA | |
| Issued Date | 2026 | |
| Abstract | Cotylelobium melanoxylon (raru) is a plant belonging to the Dipterocarpaceae family that has traditionally been used as a natural preservative for palm sap and as a herbal remedy due to its secondary metabolites with potential antioxidant properties. This study aimed to determine the chemical characteristics and antioxidant activity of (Cotylelobium melanoxylon) bark extract. The extract was obtained by maceration using 90% ethanol, followed by separation using Preparative Thin Layer Chromatography (Preparative TLC). Chemical characterization was carried out using Fourier Transform Infrared (FTIR) spectroscopy and UV-Visible spectrophotometry, while antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. The Preparative TLC analysis showed an Rf value of 0,78, while UV-Visible analysis revealed a maximum absorption wavelength of 377,847 nm, indicating the presence of flavonol compounds. FTIR characterization identified the presence of hydroxyl (O–H), aromatic C=C, and C–O functional groups, suggesting the presence of phenolic, flavonoid, and tannin compounds. The antioxidant activity assay showed an IC₅₀ value of 76,27254 µg/mL, indicating that the Cotylelobium melanoxylon bark extract exhibited strong antioxidant activity. The findings demonstrate that the extract has the potential to serve as a natural antioxidant and may be further developed as a natural raw material for pharmaceutical applications. Furthermore, this study is expected to provide a scientific basis for future research on the isolation, identification, and development of bioactive compounds from Cotylelobium melanoxylon bark as promising candidates for herbal medicines and phytopharmaceutical products that are safe, effective, and economically valuable. | 1 |
| Item Type | Skripsi | |
| Keywords | Cotylelobium melanoxylon, Karakterisasi Kimia (Chemical Characterization), FTIR (Fourier Transform Infrared), KLT Preparatif (Preparative Thin Layer Chromatography), DPPH, Antioxidant Activity, IC50 | 1 |
| Collection | Fakultas Farmasi, S1-Farmasi | |
| Publisher | INSTITUT KESEHATAN DELI HUSADA | |
| Submitted Date | 19-08-2026 | |
| Updated Date | 20-08-2026 | |
| URI | No URI | |
| File |
2218252_SONIAOCTAVIASIMANJUNTAK _SKRIPSI_S1.pdf
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