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| Advisor(s) | FAHDI, FIRDAUS | |
| Author(s) | MULIA, SYAHIDA | |
| Issued Date | 2026 | |
| Abstract | Skin infections caused by bacteria remain one of the major health problems that can lead to various skin disorders. The use of medicinal plants as natural antibacterial agents is considered a promising alternative to help overcome antibiotic resistance. Kurap mangrove leaves (Rhizophora mucronata L.) are known to contain secondary metabolites with potential antibacterial activity. This study is aimed to evaluate the antibacterial activity of the ethanolic extract of kurap mangrove leaves against Propionibacterium acnes and Staphylococcus aureus and to identify the major groups of secondary metabolites by using Thin-Layer Chromatography (TLC). The extract was obtained by maceration using 96% ethanol as the extraction solvent. TLC analysis was performed to identify three classes of secondary metabolites, namely alkaloids, flavonoids, and tannins, which are known to play important roles in inhibiting bacterial growth. Antibacterial activity was evaluated using the disc diffusion method at extract concentrations of 10%, 20%, and 30%. The results showed that the 30% extract exhibited the highest antibacterial activity, producing inhibition zones of 19.35 mm against Propionibacterium acnes and 14.60 mm against Staphylococcus aureus. It can be concluded that the ethanolic extract of kurap mangrove leaves possesses antibacterial activity against both tested bacteria, with the greatest effectiveness observed at a concentration of 30%. | 1 |
| Item Type | Skripsi | |
| Keywords | Ekstrak daun Bakau Kurap (Rhizophora mucronata L.) (Kurap Mangrove Leaf Extract (Rhizophora mucronata L.)), Kromatografi Lapis Tipis (KLT)) (Thin-Layer Chromatography (TLC)), Uji Antibakteri (Antibacterial Activity), Propionibacterium acnes (Propionibacterium acnes), Staphylococcus aureus(Staphylococcus aureus). | 1 |
| Collection | Fakultas Farmasi, S1-Farmasi | |
| Publisher | INSTITUT KESEHATAN DELI HUSADA | |
| Submitted Date | 18-08-2026 | |
| Updated Date | 18-08-2026 | |
| URI | No URI | |
| File |
2218204_SYAHIDAMULIA_SKRIPSI_S1.pdf
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