Informasi ringkas dokumen repository.
| Advisor(s) | Simorangkir, Delisma Marsauli | |
| Author(s) | KARTIKA, TRIA | |
| Issued Date | 2026 | |
| Abstract | Staphylococcus aureus infection remains a significant public health concern due to the increasing prevalence of antibiotic resistance. This condition has encouraged the exploration of natural products as alternative antibacterial agents, including papaya leaves (Carica papaya L.), which contain various secondary metabolites with potential antibacterial activity. This study is aimed to evaluate the antibacterial activity of the ethanolic extract of papaya leaves against Staphylococcus aureus by using the disk diffusion method and to determine the Minimum Inhibitory Concentration (MIC) using the broth dilution method. This laboratory experimental study employed papaya leaf extract prepared by maceration with 96% ethanol. Antibacterial activity was evaluated by using the disk diffusion method at extract concentrations of 20%, 25%, and 30%, while the MIC was determined using the broth dilution method at concentrations of 100%, 50%, 25%, 12.5%, 6.25%, and 3,125% based on changes in absorbance measured using a UV–Visible spectrophotometer. The inhibition zone diameter data were analyzed by using One-Way Analysis Of Variance (ANOVA) at a 95% confidence level. The results showed that the mean inhibition zone diameters at extract concentrations of 20%, 25%, and 30% were 8.47 mm, 9.40 mm, and 10.73 mm, respectively. The Minimum Inhibitory Concentration (MIC) of the ethanolic extract of papaya leaves was determined to be 3,125%, as indicated by a decrease in absorbance after incubation. Statistical analysis revealed a significant difference among the treatment groups (p < 0.05). In conclusion, the ethanolic extract of papaya leaves exhibited antibacterial activity against Staphylococcus aureus. Keywords: Antibacterial Activity, Carica papaya L., Ethanolic Extract Of Papaya Leaves, Minimum Inhibitory Concentration, Staphylococcus aureus. | 1 |
| Item Type | Skripsi | |
| Keywords | Aktivitas Antibakteri (Antibacterial Activity), Carica papaya L., Ekstrak Etanol Daun Pepaya ( Ethanolic Extract Of Papaya Leaves), Konsentrasi Hambat Minimum (Minimum Inhibitory Concentration), Staphylococcus aureus. | 1 |
| Collection | Fakultas Farmasi, S1-Farmasi | |
| Publisher | INSTITUT KESEHATAN DELIHUSADA DELI TUA | |
| Submitted Date | 13-08-2026 | |
| Updated Date | 13-08-2026 | |
| URI | No URI | |
| File |
2218215_TRIAKARTIKA_SKRIPSI_S1.pdf
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